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integrase

['intəgreis] імен.
мед. An enzyme found in HIV and other retroviruses. HIV uses integrase to insert integrate its viral DNA into the DNA of the host cell. Integration is a crucial step in the HIV life cycle and is targeted by a class of antiretroviral ARV HIV drugs called integrase strand transfer inhibitors INSTIs. див. також integrase strand transfer inhibitor, integration, life cycle, provirus