| genet. | dominant lethal | доминантный летальный аллель (тж. доминантная леталь – – Lethal alleles (also referred to as lethal or lethals) are alleles that cause the death of the organism that carries them. They are usually a result of mutations in genes that are essential for growth or development. Lethal alleles may be recessive, dominant, or conditional depending on the gene or genes involved. Dominant lethals Alleles that need only be present in one copy in an organism to be fatal are referred to as dominant lethal alleles. These alleles are not commonly found in populations because they usually result in the death of an organism before it can transmit its lethal allele on to its offspring. An example in humans of a dominant lethal allele is Huntington's disease, a rare neurodegenerative disorder that ultimately results in death. However, because of its late-onset (i.e., often after reproduction has already occurred), it is able to be maintained in populations. A person exhibits Huntington's disease when they carry a single copy of a repeat-expanded Huntington allele on chromosome 4.
• Наиболее продвинутый из них, называемый высвобождением насекомых, несущих доминантный летальный аллель (RIDL), стремится устранить популяции переносчиков, высвобождая самцов, несущих трансген...  wikipedia.org 'More) |