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Subject: calculated as buprenorphine free base(фарм) pharm. A depot precursor formulation comprising:a) a controlled-release matrix; b) at least oxygen containing organic solvent; c) at least 12% by weigh of at least one active agent selected from buprenorphine and salts thereof, calculated as buprenorphine free base Doses suitable for a once-weekly administration would typically be in the range 3 to 40 mg buprenorphine (calculated as buprenorphine free base), preferably 5 to 30 mg per week в перерасчете на свободное основание бупренорфина? Спасибо! |
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link 7.01.2015 20:53 |
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