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Subject: COIN trial gen. Пожалуйста, помогите перевести выражение "COIN trial".Выражение встречается в следующем контексте: "Since the results from the COIN trial have shown a higher incidence of grade ≥ 3 diarrhea, the MAH proposes to include the following interaction in the product information..." Тема: лечение метастатического колоректального рака. Заранее спасибо.
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FYI: COIN (COntinuous chemotherapy versus INtermittent chemotherapy) trial http://jco.ascopubs.org/content/28/17/e275.full |
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COIN was a randomised controlled trial in patients with previously untreated advanced colorectal cancer. Patients received either continuous oxaliplatin and fluoropyrimidine combination (arm A), continuous chemotherapy plus cetuximab (arm B), or intermittent (arm C) chemotherapy. http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(11)70102-4/abstract |
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