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 dao2812

link 16.04.2016 7:39 
Subject: for selectively altering the affinity biol.
Modifications in the CH2 domain can affect the binding of FcRs to the Fc. A number of amino acid modifications in the Fc region are known in the art ""for selectively altering"" the affinity of the Fc for different Fcgamma receptors. In some aspects, the Fc comprises one or more modifications to promote selective binding of Fc-gamma receptors.

Exemplary mutations that "alter" the binding of Fcrs to the Fc are listed below:

Как перевести "selectively altering the affinity"

Спасибо!

 

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