domain linkage (анитело) biol.

[dao2812]

the stradobody comprises, from amino to carboxy terminus, an Fab domain, an Fc domain, an IgG2 hinge, and a domain linkage

The Fc domains and/or Fc partial domains may be linked by domain linkages, as further defined herein

Domain Linkage
As indicated above, a “domain linkage” is a peptide linkage between Fc domain monomers and/or Fc partial domain monomers that comprise each of the individual stradomer monomers of the stradobodies of the present invention

Доменная или междоменная связь?

[dao2812]

может междоменный линкер?

[dao2812]

The domain linkage may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, or more amino acids. A domain linkage does not occur between Fc partial domain monomers that are in their natural sequence