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Subject: drivers of an activated PR transcriptional program (опять я) biol. there are many other PR target genes that are specifically upregulated in response to progestin treatment (i.e. the ratio of P4/ethanol). PR target genes which are induced by progestins, specifically in cells expressing activated PR (KR), compared to WT was investigated. These gene products are likely the "drivers of an activated PR transcriptional program". In fact, these types of PR genes as the ligand-dependent “KR>WT” gene signature of 151 genes (Fig. 2B, 4.1) was described.PR - progesterone receptors |
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