mutant PR (phospho-mimic) biol.

[dao2812]

Herein, a comprehensive set of experiments were performed to measure the regulation of endogenous PR target genes using current microarray techniques for whole genome expression profiling in T47D cells expressing either WT PR or SUMO-deficient mutant K388R PR (phospho-mimic), treated with or without the synthetic progestin, R5020.

PR - progesterone receptor
Как перевести phospho-mimic?

Спасибо!

[ramix]

mimic = mimetic > миметический (подражательный)
получается фосфомиметический, но слово почти не встречается в гугле

[dao2812]

может фосфомиметик?

[dao2812]

Есть еще словосочетание "functional mimic"

Multiple clones were engineered of vector-matched PR-null T47D breast cancer cells expressing either wild-type (WT) PR-B or mutant K388R (KR) PR-B that is unable to undergo SUMO modification at Lys388; this SUMO-deficient receptor is a "functional mimic" for PR-B that is persistently phosphorylated on Ser294 (Daniel et al., 2007a; Lange et al., 2000).