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 irina-de

link 20.10.2014 17:03 
Subject: FGE/aldehyde tag technology pharma.
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FGE/aldehyde tag technology

Контекст:

Together they developed bioconjugates that incorporate Redwood’s proprietary FGE/aldehyde tag technology and novel bioconjugation chemistry.

 гарпия

link 22.10.2014 1:40 
FGE-formylglycine generating enzyme

FGE recognizes consensus sequence CxPxR and specifically oxidizes the cysteine in the sequence to aldehyde-bearing formylglycine

FGE recognition sequence, or aldehyde tag can be inserted into recombinant proteins

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498491/
т.е. по сути FGE/aldehyde tag technology есть рекомбинантная технология с внедрением последовательности, распознаваемой формилглицин образующим ферментом

 

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