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link 9.09.2014 13:31 |
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Subject: "knob and hole" heavy chains what means, please answer gen. "knob and hole" please answer what means in context of heavy chains
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The helices of the TPR motives have usually amphipathic character. Hydrophobic contacts with an aromatic residue phenylalanin from helix B fitting into a hydrophobic pocket in helix A pack the helices together. This is also known as “knob and hole” model. |
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link 9.09.2014 13:58 |
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Thank you very much, pleaseq can you ask me how will call this in russian knob and hole Спасибо, очень.....have a nice day.... |
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есть по типу «выступ и впадина» (“knob-and-hole”) http://www.findpatent.ru/patent/240/2404991.html но есть и оставленное на англ. Для BsIgG требуются разработанные "knob and hole" тяжелые цепи для предотвращения образования гетеродимеров http://www.findpatent.ru/patent/239/2398882.html второе звучит неуклюже |
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