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слететь с катушек stresses
gen.	get off the trolley (alenushpl); get off one's trolley (alenushpl); go off trolley (alenushpl)
Игорь Миг	go crazy; get unhinged; get mad
amer.	go hyphy (act ignorant with a large group of people or start fights Val_Ships); off one's rocker (slang Val_Ships)
fig.	fly off the handle (Damirules); come unglued (igisheva)
idiom.	lose it (Баян); go off the rails (to start behaving strangely or in a way that is not acceptable to society: "She went off the rails in her early teens after she moved in with her 25-year-old boyfriend and started smoking pot, soon she living on the streets and got involved in sex trade." ART Vancouver); go haywire (Vadim Rouminsky)
inf.	go to pieces (Morning93); run mad (Andrey Truhachev); go mad (Andrey Truhachev); go bats (Andrey Truhachev); go nuts (Andrey Truhachev); freak out (Abysslooker); have a meltdown (if someone doesn't fix the elctricity in the computer room i might have a meltdown. chronik); snap (потерять разум, потерять контроль над собой SvezhentsevaMaria)
jarg.	get spastic (igisheva); go spastic (igisheva); blow a gasket (igisheva); blow a fuse (igisheva)
nonstand.	go crackers (resurcat)
psychol.	crack up coll. (Andrey Truhachev)
slang	lose one's marbles; loopity-doopity-doopy (psylingua); go a little nuts (Himera); go off the deep end (Баян); gone off the deep end (Rust71); fly off the wall (Mira_G); blow one's gasket (VLZ_58); go ballistic (в знач. "разозлиться" Lavrin); go bitchcakes (SirReal); pop one's cork (plushkina); go tonto (Val_Ships)
vulg.	go apeshit (4uzhoj)
слетевший с катушек
gen.	unhinged (Taras)
inf.	unhinged (Баян)
slang	bonkers (Rust71)

слететь с катушек: 8 phrases in 4 subjects

General	3
Idiomatic	3
Informal	1
Slang	1