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взяться за дело stresses
gen.	tackle the problem; get down to business; get on the stick; put hand to; put hand to the plough; put hand to the plow; set about one's work (bookworm); spring into action (Aly19); come down to business; get cracking; get going; get moving; get started; set one's hand to (eugenealper); get weaving; buckle down (VLZ_58); pounce (Movie studios are ready to pounce as soon as she announces that she's making movies again. VLZ_58); not mess about (в контексте 4uzhoj)
Игорь Миг	get the ball rolling; set the ball rolling; take on the task
amer.	up and at them (обычно используется в виде команды Taras); up and at 'em (обычно используется в виде команды Taras)
idiom.	knuckle down (This week I am going to knuckle down & really stick to it, as close as I can. 4uzhoj)
Makarov.	come down to bedrock; come to business; get down to bedrock; get down to work; set one's hand to the plough; turn to
poetic	go about work (Andrey Truhachev)
slang	get down to it (Баян)
взяться за какое-либо дело
Makarov.	settle down to something; settle down to do something; settle to something; settle to do something

взяться за дело: 69 phrases in 9 subjects

American usage, not spelling	3
General	34
Idiomatic	3
Informal	1
Makarov	21
Mass media	2
Rail transport	1
Slang	3
Sports	1