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provirus [prəʊ'vai(ə)rəs] n
med. HIV DNA that has integrated into the DNA of the host cell. When HIV enters a host cell, HIV RNA is first changed to HIV DNA provirus. The provirus then gets inserted into the DNA of the host cell. When the host cell replicates, the HIV provirus is passed from one cell generation to the next, ensuring ongoing replication of HIV see also integration