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cytochromes P450
gen. Cytochrome P450 CYP
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Cytochrome P450 CYP450
med. A group of enzymes involved in the breakdown of drugs in the liver. Many drugs can inhibit or enhance the activity of these enzymes, causing drug levels in the blood to increase or decrease. Cytochrome P450 CYP450 enzymes metabolize all protease inhibitors PIs and non-nucleoside reverse transcriptase inhibitors NNRTIs and can cause drug interactions that may result in adverse effects. see also drug interaction