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dual-tropic virus
med. A strain of HIV that can enter and infect a host cell by binding to either the CCR5 or CXCR4 receptor on the host cell. To enter a host cell, HIV must first attach to a CD4 receptor, then attach to either the CCR5 or CXCR4 receptor, and finally fuse its membrane with the host cell membrane. HIV is usually R5-tropic uses CCR5 during the early stages of infection, but the virus may later switch to using either only CXCR4 or both CCR5 and CXCR4. see also CCR5, CXCR4, R5-tropic virus, X4-tropic virus
dual: 394 phrases in 47 subjects
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