разговор "за жизнь"(He took on every project with a smile, and his door was always open for a conversation about creative strategy or for a good heart-to-heart about life.)
поговорить по душам(a talk or discussion in which two people talk honestly and in a serious way about their feelings (Cambridge Dictionary)ART Vancouver)
поговорить начистоту(a talk or discussion in which two people talk honestly and in a serious way about their feelings (Cambridge Dictionary) ART Vancouver)
задушевный разговор(The heavens are conspiring to bring you even closer to your friends than you have been – which is really saying something. In fact, you could end up in a long heart-to-heart with someone you've been dying to make peace with VLZ_58)