de-drugging pharm.

[Cheshire136]

Пожалуйста, помогите перевести de-drugging в следующем предложении.

Both, the above-mentioned serum instability and the heterogeneity of chemically conjugated, and maleimide-linker containing BPDCs or ADCs represent significant liabilities for the safety of these drugs in cancer patients, because both add to the non-specific release of the toxin ("de-drugging") of such ADCs in patients.

[Petrelnik]

1. Передайте мое возмущение авторам. Фу так писать.
2. Расшифруйте сокращения, пжалста.

[Cheshire136]

binding protein drug conjugates — BPDCs
antibody drug conjugates — ADCs