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Subject: Absent from outer layer polym. The polymeric drug-device unit may further comprise an outer layer as a sheath or coating which fully, substantially or at least partially covers or envelopes the inner core structure or layer. The outer layer may comprise, consist essentially or consist of one or more of the polymeric block copolymers described herein. The inner core structure or layer may comprise the active agent (for example quinagolide). The active agent may be absent from the outer layer, sheath or coating. Without wishing to be bound by theory, it is believed that an advantage of such a reservoir type structure is that it can significantly improve the control of the initial and long term release characteristics of the device.The active agent may be absent from the outer layer? Как это понять? Это то, что активный агент не находится со стороны этого внешнего слоя или он не защищён таким слоем? Помогите разобраться и понять смысл этого фрагмента: The active agent may be absent from the outer layer, sheath or coating. Спасибо!
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