Subject: complementary to each other in defining faster versus normal clearance biol. Next, it was examined to determine if pI (and/or charge) and hydrophobicity ""were complementary to each other in defining faster versus normal clearance"". Also explored was whether charge at a certain pH would be more discriminating with respect to clearance values (antibody clearance involves neonatal Fc receptor salvation through the endosomal environment that has low pH, pH 5 – 6 (where Fc is a C-terminal region of an antibody heavy chain that contains at least a portion of the constant region))Furthermore, it appeared that the charge and selective HI of CDRs ""were complementary to each other"" in differentiating faster clearing mAbs, i.e. those mAbs with charge values between 0.4 and 6.1 in the fast clearance group had a relatively higher HI sum. Как перевести в данном контексте complementary to each other.. спасибо! |
да как и везде в общем - взаимодополняют |
Furthermore, it appeared that the charge and selective HI of CDRs ""were complementary to each other"" in differentiating faster clearing mAbs, i.e. those mAbs with charge values between 0.4 and 6.1 in the fast clearance group had a relatively higher HI sum. Кроме того, оказалось, что заряд и избирательный HI CDR взаимодополняли друг друга в отношении отличия мАт с более быстрым клиренсом, т.е. для мАт со значеними заряда в пределах от 0,4 до 6,1 в группе с быстрым клиренсом сума значений HI была относительно больше? |
every problem is a disguised opportunity поглубже копнете в свою предметную область сегодня - полегче будет назавтра |
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