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Subject: mutagenizing the light chain and/or heavy chain variable region amino acid sequence biol.
For each embodiment described herein, the methods may further comprise the step of mutagenizing one or more amino acid residues of the light chain and/or heavy chain variable region amino acid sequence of the antibody to generate a target antibody when the index exceeds the viscosity limit.""The step of mutagenizing the light chain and/or heavy chain variable region amino acid sequence"" may reduce hydrophobicity, increases net charge, and/or increase or decrease charge asymmetry so that the index of the target antibody does not exceed the viscosity limit. The method may further comprise the step of producing the target antibody. Как перевести в данном контексте "The step of mutagenizing the light chain and/or heavy chain variable region amino acid sequence" Спасибо!
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