Subject: log-scale data (биоинформатика) biol. Gene set enrichment analysis (GSEA) software (Mootha et al., 2003; Subramanian et al., 2005) was employed to compare genes up- or downregulated in cells stably expressing WT or KR PR to cells expressing inducible iWT or iKR PR.
GSEA was executed using the default settings, except the permutation type was set to Gene_set with 1000 permutations, and the metric for ranking genes was set to Diff_of_Classes because our dataset contained log-scale data Спасибо!
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