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имхо, пространственная близость подойдет см.
Bioluminescence Resonance Energy Transfer (BRET) improves the sensitivity of bioluminescence by red-shifting blue photons, and provides a measure of molecular ****co-localization at distances of up to 10nm. However, BRET detection methods may overlook long-distance, radiating energy excitation-emission effects that are significant in the bioluminescent detection regime. Fluorescence by Unbound Excitation from Luminescence (FUEL) describes this radiating luminescence effect that excites fluorophores by epifluorescence *****at distances far beyond 10nm, many microns, or even millimeters away in a manner completely distinct from BRET. Further, we show that detection of FUEL per se is sufficient to provide a ****detection of long-distance proximity in, and beyond the microscopic range both in vitro and in vivo. By enabling detection of mesoscopic proximity between luminescent and fluorescent probes in the context of living biological tissues FUEL promises utility as a novel tool for high-content analysis in cell and animal models.
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