impairment, damage or disruption in his body function or structure, pharm.

[Natuli]

Подскажите, пожалуйста, как здесь перевести "impairment, damage or disruption in his body function or structure"
The term “disability/incapacity” means that following the event the subject or clinical investigation subject has significant, persistent or permanent change, impairment, damage or disruption in his body function or structure, physical activity and/or quality of life.

[Dimpassy]

нарушение функции, дегенеративные изменения или механическое повреждение анатомических структур организма

[Natuli]

большое спасибо, звучит как -то устращающее, но красивей не придумать..