Type of Study - Metabolic potency of insulin ХХХ in L6-hIR cells. Method of Administration- Glycogen synthesis in L6-hIR cells in response to increasing concentrations of insulin or insulin ХХХ was determined using 14C-glucose to allow assessment of glucose incorporation into glycogen. The assay was conducted in the presence of 0.1% HSA.Doses -Dose response profiles were obtained in the range of 0-100 nM insulin ХХХ. Noteworthy Findings and Conclusions - In the presence of 0.1% albumin, the estimated potencies ranged from 2.7 to 5.2% and the combined potency was calculated as being 4.4% (3.2 – 6.0%, 95% confidence interval). Noteworthy Findings and Conclusions-
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